For molecular characterization of the CTCs, blood needs to be processed using the ScreenCell MB kit. At the end of the isolation process, living CTC retained on the isolation support are ready for cell lysis, directly on the capsule. Thus, MB capsule lead to CTC genome and transcriptome access and open many downstream applications such as
– NGS (DNA / RNAseq)
ScreenCell MB Kit is compatible with different DNA/RNA extraction kits. Ask for protocol and further information.
Moreover, ScreenCell technology allows parallel molecular biology studies on CTC and cfDNA from the same blood sample.